STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR36469.1Methicillin resistance protein; COGs: COG2348 Uncharacterized protein involved in methicillin resistance; InterPro IPR003447; KEGG: msv:Mesil_2093 methicillin resistance protein; PFAM: Methicillin resistance protein; SPTR: Methicillin resistance protein; PFAM: FemAB family. (357 aa)    
Predicted Functional Partners:
ruvA
Holliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
       0.795
ADR35707.1
VanW family protein; COGs: COG2720 Uncharacterized vancomycin resistance protein; InterPro IPR007391: IPR013838; KEGG: ttj:TTHA0072 hypothetical protein; PFAM: VanW family protein; SPTR: Vancomycin B-type resistance protein vanW; PFAM: VanW like protein.
  
     0.682
ADR37617.1
UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR020026: IPR000653; KEGG: svi:Svir_01560 predicted PLP-dependent enzyme possibly involved in cell wall biogenesis; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; PRIAM: Glutamine--scyllo-inositol transaminase; SPTR: Predicted PLP-dependent enzyme possibly involved in cell wall biogenesis; TIGRFAM: UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; TIGR [...]
      0.602
pheA
COGs: COG0077 Prephenate dehydratase; InterPro IPR001086: IPR018528: IPR002912; KEGG: ttj:TTHA1104 prephenate dehydratase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; PRIAM: Prephenate dehydratase; SPTR: Prephenate dehydratase; PFAM: Prephenate dehydratase; ACT domain.
       0.567
ADR36468.1
ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
       0.553
ADR37107.1
COGs: COG1963 conserved hypothetical protein; InterPro IPR003832; KEGG: mrb:Mrub_2370 acid phosphatase/vanadium-dependent haloperoxidase-like protein; PFAM: acid phosphatase/vanadium-dependent haloperoxidase related; SPTR: Acid phosphatase/vanadium-dependent haloperoxidase related protein; PFAM: Divergent PAP2 family.
 
     0.409
murE
UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
 
  
 0.403
Your Current Organism:
Oceanithermus profundus
NCBI taxonomy Id: 670487
Other names: O. profundus DSM 14977, Oceanithermus profundus DSM 14977, Oceanithermus profundus str. DSM 14977, Oceanithermus profundus strain DSM 14977
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.