STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (434 aa)    
Predicted Functional Partners:
glmU
Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
 
 0.994
glmS
Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
 
 0.952
ADR37345.1
Glutamine--fructose-6-phosphate transaminase; COGs: COG2222 phosphosugar isomerase; InterPro IPR001347; KEGG: msv:Mesil_0290 glutamine--fructose-6-phosphate transaminase (isomerizing); PFAM: sugar isomerase (SIS); PRIAM: Glutamine--fructose-6-phosphate transaminase (isomerizing); SPTR: Glutamine--fructose-6-phosphate transaminase (Isomerizing); PFAM: SIS domain.
 
 
  0.920
ADR37346.1
COGs: COG1820 N-acetylglucosamine-6-phosphate deacetylase; InterPro IPR003764: IPR006680; KEGG: msv:Mesil_0289 N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; PRIAM: N-acetylglucosamine-6-phosphate deacetylase; SPTR: N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: Amidohydrolase family; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase.
     
 0.914
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.804
ADR36515.1
Thioesterase superfamily protein; COGs: COG0824 thioesterase; InterPro IPR006684: IPR006683; KEGG: tra:Trad_1382 thioesterase superfamily protein; PFAM: thioesterase superfamily protein; SPTR: Thioesterase superfamily protein; PFAM: Thioesterase superfamily; TIGRFAM: acyl-CoA thioester hydrolase, YbgC/YbaW family.
       0.725
rbfA
Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
       0.724
ADR36511.1
Uncharacterized protein family UPF0029, Impact, N-terminal protein; COGs: COG1739 conserved hypothetical protein; InterPro IPR020569: IPR001498; KEGG: msv:Mesil_2225 protein of unknown function UPF0029; PFAM: Uncharacterised protein family UPF0029, Impact, N-terminal; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized protein family UPF0029; TIGRFAM: uncharacterized protein, YigZ family.
  
    0.716
ADR36509.1
COGs: COG0169 Shikimate 5-dehydrogenase; InterPro IPR011342: IPR013708: IPR006151; KEGG: mrb:Mrub_1819 shikimate 5-dehydrogenase; PFAM: Shikimate dehydrogenase substrate binding domain protein; Shikimate/quinate 5-dehydrogenase; SPTR: Shikimate 5-dehydrogenase; TIGRFAM: shikimate 5-dehydrogenase; PFAM: Shikimate dehydrogenase substrate binding domain; Shikimate / quinate 5-dehydrogenase; TIGRFAM: shikimate 5-dehydrogenase.
     
 0.710
ADR35723.1
Hypothetical protein; Displays ATPase and GTPase activities.
 
   
 0.705
Your Current Organism:
Oceanithermus profundus
NCBI taxonomy Id: 670487
Other names: O. profundus DSM 14977, Oceanithermus profundus DSM 14977, Oceanithermus profundus str. DSM 14977, Oceanithermus profundus strain DSM 14977
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.