STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
recRDNA replication and repair protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (197 aa)    
Predicted Functional Partners:
ADR36328.1
Recombination protein O RecO; Involved in DNA repair and RecF pathway recombination.
  
 
 0.985
ADR36832.1
Uncharacterized protein family UPF0133; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
  
  
 0.976
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
    
 0.874
ADR36827.1
KEGG: msv:Mesil_1375 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3467).
 
     0.790
ADR36829.1
KEGG: msv:Mesil_1377 roadblock/LC7 family protein; SPTR: Roadblock/LC7 family protein; PFAM: Roadblock/LC7 domain.
       0.790
ADR36830.1
KEGG: dge:Dgeo_1018 roadblock/LC7 domain-contain protein; SPTR: Putative uncharacterized protein.
       0.781
ADR36828.1
Roadblock/LC7 family protein; InterPro IPR004942; KEGG: mrb:Mrub_1151 roadblock/LC7 family protein; PFAM: Roadblock/LC7 family protein; SPTR: Roadblock/LC7 family protein; PFAM: Roadblock/LC7 domain.
       0.755
recF
DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.
 
  
 0.746
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
 0.689
ADR35760.1
PSP1 domain protein; COGs: COG1774 Uncharacterized homolog of PSP1; InterPro IPR007557; KEGG: msv:Mesil_0647 PSP1 domain protein; PFAM: PSP1 domain protein; SPTR: PSP1 domain protein; PFAM: PSP1 C-terminal conserved region.
      0.661
Your Current Organism:
Oceanithermus profundus
NCBI taxonomy Id: 670487
Other names: O. profundus DSM 14977, Oceanithermus profundus DSM 14977, Oceanithermus profundus str. DSM 14977, Oceanithermus profundus strain DSM 14977
Server load: low (16%) [HD]