STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR36847.1KEGG: mrb:Mrub_2742 hypothetical protein; SPTR: Putative uncharacterized protein. (285 aa)    
Predicted Functional Partners:
ADR36844.1
COGs: COG4972 Tfp pilus assembly protein ATPase PilM; InterPro IPR005883; KEGG: msv:Mesil_1336 type IV pilus assembly protein PilM; SPTR: Type IV pilus assembly protein PilM; TIGRFAM: type IV pilus assembly protein PilM; PFAM: Competence protein A; Cell division protein FtsA; TIGRFAM: type IV pilus assembly protein PilM.
     
 0.859
ADR36845.1
Fimbrial assembly family protein; InterPro IPR007813; KEGG: mrb:Mrub_2740 hypothetical protein; PFAM: Fimbrial assembly family protein; SPTR: Putative uncharacterized protein; PFAM: Fimbrial assembly protein (PilN).
     
 0.859
ADR36846.1
General secretion pathway protein M; InterPro IPR019677; KEGG: mrb:Mrub_2741 hypothetical protein; PFAM: General secretion pathway protein M; SPTR: Putative uncharacterized protein; PFAM: General secretion pathway protein M.
     
 0.859
ADR36848.1
Type II and III secretion system protein; COGs: COG1450 Type II secretory pathway component PulD; InterPro IPR005644: IPR004846: IPR001775; KEGG: tth:TTC1017 competence protein PilQ; PFAM: type II and III secretion system protein; NolW domain protein; SPTR: Competence protein pilQ; PFAM: Bacterial type II/III secretion system short domain; Bacterial type II and III secretion system protein.
  
  
 0.798
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
       0.590
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
       0.588
ADR36851.1
COGs: COG0337 3-dehydroquinate synthetase; InterPro IPR016303: IPR002658; KEGG: tth:TTC1020 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase; PRIAM: 3-dehydroquinate synthase; SPTR: 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase; TIGRFAM: 3-dehydroquinate synthase.
       0.580
aroQ
3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
       0.572
ADR36843.1
COGs: COG0473 Isocitrate/isopropylmalate dehydrogenase; InterPro IPR001804: IPR019818; KEGG: msv:Mesil_1337 3-isopropylmalate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase; PRIAM: 3-isopropylmalate dehydrogenase; SPTR: 3-isopropylmalate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: 3-isopropylmalate dehydrogenase; isopropylmalate/isohomocitrate dehydrogenases.
       0.518
ADR37691.1
DNA internalization-related competence protein ComEC/Rec2; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004797: IPR004477; KEGG: msv:Mesil_3192 DNA internalization-related competence protein ComEC/Rec2; PFAM: ComEC/Rec2-related protein; SPTR: DNA internalization-related competence protein ComEC/Rec2; TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2.
  
  
 0.479
Your Current Organism:
Oceanithermus profundus
NCBI taxonomy Id: 670487
Other names: O. profundus DSM 14977, Oceanithermus profundus DSM 14977, Oceanithermus profundus str. DSM 14977, Oceanithermus profundus strain DSM 14977
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