STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ADR36864.1Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: ttj:TTHA1641 GGDEF domain-containing protein; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: Diguanylate cyclase/phosphodiesterase domain 1 (GGDEF); TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (346 aa)    
Predicted Functional Partners:
ADR35602.1
Metal dependent phosphohydrolase; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR006674; KEGG: tra:Trad_1982 diguanylate cyclase and metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SPTR: Diguanylate cyclase and metal dependent phosphohydrolase; PFAM: HD domain.
 
  
 0.976
ADR36841.1
Metal dependent phosphohydrolase; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR003607: IPR006674; KEGG: msv:Mesil_1339 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Metal dependent phosphohydrolase; manually curated; PFAM: HD domain.
 
 
 0.973
ADR37633.1
Putative PAS/PAC sensor protein; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterProIPR000834: IPR000014: IPR003018: IPR003607: IPR 013767: IPR013655: IPR006674: IPR000700; KEGG: tth:TTC0629 HD-hydrolase domain-containing protein; PFAM: metal-dependent phosphohydrolase HD sub domain; PAS fold-3 domain protein; PAS fold domain protein; GAF domain protein; SMART: metal-dependent phosphohydrolase HD region; GAF domain protein; PAS domain containing protein; SPTR: HD-hydrolase domain; TIGRFAM: PAS sensor protein; PFAM: HD domain; PAS fold; [...]
 
 0.893
ADR36361.1
Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR006675: IPR003018: IPR003607: IPR006674; KEGG: msv:Mesil_3117 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; GAF domain protein; SMART: metal-dependent phosphohydrolase HD region; GAF domain protein; SPTR: Metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; GAF domain; TIGRFAM: uncharacterized domain HDIG.
 
 0.848
ADR37423.1
Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR003607; KEGG: adg:Adeg_0458 metal dependent phosphohydrolase; SMART: metal-dependent phosphohydrolase HD region; SPTR: Metal dependent phosphohydrolase; PFAM: HD domain.
  
 
 0.765
ADR36072.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterProIPR000014: IPR000160: IPR001610: IPR003018: IPR 001633: IPR000700: IPR013655; KEGG: ddr:Deide_1p00099 putative diguanylate-cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; PAS fold-3 domain protein; GAF domain protein; SMART: EAL domain protein; GGDEF domain containing protein; GAF domain protein; PAC repeat-containing protein; PAS domain containing protein; SPTR: Putative diguanylate-cyclase; [...]
 
0.729
ADR36865.1
Cys/Met metabolism pyridoxal-phosphate-dependent protein; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: rle:pRL110363 hypothetical protein; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: Putative methionine lyase; PFAM: Cys/Met metabolism PLP-dependent enzyme.
       0.709
ADR35575.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterProIPR003018: IPR013767: IPR000160: IPR001633: IPR 000014; KEGG: app:CAP2UW1_4053 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain protein; GGDEF domain containing protein; GAF domain protein; PAS fold domain protein; SMART: GGDEF domain containing protein; PAS domain containing protein; GAF domain protein; EAL domain protein; SPTR: Diguanylate cyclase/phosphodiesterase with GAF sensor; [...]
 
 
0.699
ADR36866.1
KEGG: tga:TGAM_0987 hypothetical protein; SPTR: Trichohyalin, putative.
       0.660
ADR35626.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterProIPR013655: IPR003018: IPR013656: IPR000160: IPR 001633: IPR000014: IPR001610: IPR000700; KEGG: ava:Ava_2710 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain protein; GGDEF domain containing protein; PAS fold-3 domain protein; GAF domain protein; PAS fold-4 domain protein; SMART: EAL domain protein; GGDEF domain containing protein; GAF domain protein; PAS domain containing protein; PA [...]
 
0.625
Your Current Organism:
Oceanithermus profundus
NCBI taxonomy Id: 670487
Other names: O. profundus DSM 14977, Oceanithermus profundus DSM 14977, Oceanithermus profundus str. DSM 14977, Oceanithermus profundus strain DSM 14977
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