STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR37116.1TPR repeat-containing protein; InterPro IPR013026: IPR019734; KEGG: msv:Mesil_2447 TPR repeat-containing protein; SPTR: TPR repeat-containing protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2325). (932 aa)    
Predicted Functional Partners:
ADR37117.1
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006140: IPR006139; KEGG: msv:Mesil_1507 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain.
   
   0.776
ADR37118.1
GCN5-related N-acetyltransferase; COGs: COG1670 Acetyltransferase including N-acetylase of ribosomal protein; InterPro IPR000182; KEGG: msv:Mesil_1506 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family.
  
    0.771
ADR37115.1
Transketolase; COGs: COG0021 Transketolase; InterPro IPR005474: IPR005475: IPR005476: IPR005478; KEGG: mrb:Mrub_1828 transketolase; PFAM: Transketolase domain-containing protein; Transketolase central region; SPTR: Transketolase; TIGRFAM: transketolase; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; TIGRFAM: transketolase, bacterial and yeast; Belongs to the transketolase family.
   
 
 0.703
ADR37114.1
KEGG: mrb:Mrub_1830 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.697
efp
Translation elongation factor P (EF-P); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
  
   0.643
ADR37111.1
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
   
   0.642
ADR37112.1
Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
       0.629
ADR37119.1
COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR006095: IPR006097: IPR006096: IPR014362; KEGG: mrb:Mrub_0389 glu/Leu/Phe/Val dehydrogenase; PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; SPTR: Glu/Leu/Phe/Val dehydrogenase; PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
       0.601
ADR37120.1
COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterProIPR020082: IPR006097: IPR006096: IPR006095: IPR 014362; KEGG: msv:Mesil_1504 glutamate dehydrogenase (NAD(P)(+)); PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; SPTR: Glutamate dehydrogenase (NAD(P)(+)); PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
       0.601
nusB
NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
       0.570
Your Current Organism:
Oceanithermus profundus
NCBI taxonomy Id: 670487
Other names: O. profundus DSM 14977, Oceanithermus profundus DSM 14977, Oceanithermus profundus str. DSM 14977, Oceanithermus profundus strain DSM 14977
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