STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR37153.1Glucokinase; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: msv:Mesil_2974 ROK family protein; PFAM: ROK family protein; SPTR: ROK family protein; PFAM: ROK family; TIGRFAM: ROK family protein (putative glucokinase). (301 aa)    
Predicted Functional Partners:
pgi
COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR001672: IPR018189; KEGG: mrb:Mrub_2801 phosphoglucose isomerase (PGI); PFAM: phosphoglucose isomerase (PGI); SPTR: Glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase; Belongs to the GPI family.
 
 
 0.937
ADR37619.1
Mannose-6-phosphate isomerase, type 1; COGs: COG1482 Phosphomannose isomerase; InterPro IPR014628: IPR001250; KEGG: msv:Mesil_0920 mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type I; PRIAM: Mannose-6-phosphate isomerase; SPTR: Mannose-6-phosphate isomerase; PFAM: Phosphomannose isomerase type I; TIGRFAM: mannose-6-phosphate isomerase, class I.
 
  
 0.923
ADR35750.1
HAD-superfamily hydrolase, subfamily IA, variant 3; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834: IPR005833: IPR006402: IPR006439; KEGG: dge:Dgeo_1288 HAD family hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: HAD-superfamily hydrolase subfamily IA, variant 3; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Epoxide hydrolase N-terminal dom [...]
   
 
  0.904
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.852
ADR35913.1
COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771: IPR011289; KEGG: ttj:TTHA1773 fructose-1,6-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Fructose-bisphosphate aldolase; SPTR: Fructose-1,6-bisphosphate aldolase; TIGRFAM: fructose-1,6-bisphosphate aldolase, class II; ketose-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist.
    
 0.848
ADR37115.1
Transketolase; COGs: COG0021 Transketolase; InterPro IPR005474: IPR005475: IPR005476: IPR005478; KEGG: mrb:Mrub_1828 transketolase; PFAM: Transketolase domain-containing protein; Transketolase central region; SPTR: Transketolase; TIGRFAM: transketolase; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; TIGRFAM: transketolase, bacterial and yeast; Belongs to the transketolase family.
  
 
 0.842
ADR37218.1
COGs: COG2379 Putative glycerate kinase; InterPro IPR013838: IPR000897: IPR007835; KEGG: msv:Mesil_1425 hydroxypyruvate reductase; PFAM: MOFRL domain protein; PRIAM: Hydroxypyruvate reductase; SPTR: Hydroxypyruvate reductase; PFAM: MOFRL family.
    
  0.814
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
    
  0.806
ADR37636.1
Transketolase central region; COGs: COG3958 Transketolase C-terminal subunit; InterPro IPR005475: IPR005476; KEGG: tle:Tlet_1683 transketolase central region; PFAM: Transketolase central region; Transketolase domain-containing protein; SPTR: Transketolase central region; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.
     
  0.800
ADR37637.1
Transketolase domain-containing protein; COGs: COG3959 Transketolase N-terminal subunit; InterPro IPR005474; KEGG: tle:Tlet_1682 transketolase domain-containing protein; PFAM: Transketolase domain-containing protein; SPTR: Transketolase domain protein; PFAM: Transketolase, thiamine diphosphate binding domain.
    
  0.800
Your Current Organism:
Oceanithermus profundus
NCBI taxonomy Id: 670487
Other names: O. profundus DSM 14977, Oceanithermus profundus DSM 14977, Oceanithermus profundus str. DSM 14977, Oceanithermus profundus strain DSM 14977
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