STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR37348.1COGs: COG2272 Carboxylesterase type B; InterPro IPR002018: IPR000997; KEGG: mrb:Mrub_0723 carboxylesterase; PFAM: Carboxylesterase type B; SPTR: Carboxylesterase; PFAM: Carboxylesterase. (517 aa)    
Predicted Functional Partners:
ADR35909.1
Peptidase M28; KEGG: msv:Mesil_0757 peptidase M28; SPTR: Peptidase M28; PFAM: Peptidase family M28.
  
 0.844
rpsD
SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
    
  0.842
ADR35549.1
SSU ribosomal protein S1P; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
   
 
  0.827
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
   
 0.819
rpsK
SSU ribosomal protein S11P; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
    
  0.815
ADR35782.1
COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR011545: IPR001650: IPR014021: IPR014014: IPR 000629: IPR014001; KEGG: tra:Trad_2113 DEAD/DEAH box helicase domain protein; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: DEAD/DEAH box helicase domain protein; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; Belongs to the DEAD box helicase family.
   
 0.813
plsX
Phosphate:acyl-(acyl carrier protein) acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
 
     0.800
ADR37349.1
COGs: COG0668 Small-conductance mechanosensitive channel; InterPro IPR006685; KEGG: mrb:Mrub_2054 MscS mechanosensitive ion channel; PFAM: MscS Mechanosensitive ion channel; SPTR: MscS Mechanosensitive ion channel; PFAM: Mechanosensitive ion channel.
       0.773
ADR37351.1
Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterProIPR017936: IPR017937: IPR005746: IPR013766: IPR 006662; KEGG: msv:Mesil_3022 thioredoxin; PFAM: Thioredoxin domain-containing protein; SPTR: Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin; Belongs to the thioredoxin family.
       0.773
ADR37440.1
HRDC domain protein; InterPro IPR002121; KEGG: car:cauri_1389 hypothetical protein; PFAM: HRDC domain protein; SPTR: Putative membrane protein.
    
  0.737
Your Current Organism:
Oceanithermus profundus
NCBI taxonomy Id: 670487
Other names: O. profundus DSM 14977, Oceanithermus profundus DSM 14977, Oceanithermus profundus str. DSM 14977, Oceanithermus profundus strain DSM 14977
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.