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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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rlmN23S rRNA m(2)A-2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (370 aa)    
Predicted Functional Partners:
miaB
tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
 
  
 0.745
ADR37022.1
Fmu (Sun) domain protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR006650: IPR018314: IPR001678; KEGG: mrb:Mrub_1306 RNA methylase NOL1/NOP2/sun family; PFAM: Fmu (Sun) domain protein; SPTR: RNA methylase, NOL1/NOP2/sun family; PFAM: NOL1/NOP2/sun family; TIGRFAM: NOL1/NOP2/sun family putative RNA methylase.
  
  
 0.707
ADR36233.1
RNA modification enzyme, MiaB family; COGs: COG0621 2-methylthioadenine synthetase; InterProIPR020612: IPR005839: IPR006467: IPR006638: IPR 002792: IPR013848: IPR006158: IPR007197; KEGG: msv:Mesil_2352 MiaB-like tRNA modifying enzyme; PFAM: protein of unknown function UPF0004; cobalamin B12-binding domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: MiaB-like tRNA modifying enzyme; TIGRFAM: RNA modification enzyme, MiaB family; MiaB-like tRNA modifying enzyme; PFAM: Radical SAM superfamily; B12 binding domain; Uncharacterized protein family UPF0004; [...]
 
  
 0.702
ADR37043.1
Coproporphyrinogen III oxidase, anaerobic; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
 
   
 0.690
ADR36628.1
NusB/RsmB/TIM44; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR020559: IPR006027: IPR001678; KEGG: ttj:TTHA0851 Sun protein (RNA methyltransferase); PFAM: NusB/RsmB/TIM44; Fmu (Sun) domain protein; SPTR: Sun protein (RNA methyltransferase); PFAM: NOL1/NOP2/sun family; NusB family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
  
 0.602
ADR35752.1
COGs: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR007197: IPR010723: IPR006638; KEGG: sat:SYN_01802 coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; PRIAM: Coproporphyrinogen dehydrogenase; SMART: Elongator protein 3/MiaB/NifB; SPTR: Coproporphyrinogen oxidase (NAD); PFAM: Radical SAM superfamily; HemN C-terminal region.
 
   
 0.601
ADR37431.1
Small multidrug resistance protein; COGs: COG2076 Membrane transporter of cations and cationic drugs; InterPro IPR000390; KEGG: bur:Bcep18194_A4701 small multidrug resistance protein; PFAM: small multidrug resistance protein; SPTR: Putative mebrane transport protein; PFAM: Small Multidrug Resistance protein.
       0.575
ADR36294.1
Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
 
     0.574
ADR37432.1
InterPro IPR000866; KEGG: dge:Dgeo_1960 hypothetical protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: Thioredoxin; PFAM: AhpC/TSA family.
       0.552
ADR37172.1
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.535
Your Current Organism:
Oceanithermus profundus
NCBI taxonomy Id: 670487
Other names: O. profundus DSM 14977, Oceanithermus profundus DSM 14977, Oceanithermus profundus str. DSM 14977, Oceanithermus profundus strain DSM 14977
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