Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADR37432.1InterPro IPR000866; KEGG: dge:Dgeo_1960 hypothetical protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: Thioredoxin; PFAM: AhpC/TSA family. (150 aa)    
Predicted Functional Partners:
ADR37431.1
Small multidrug resistance protein; COGs: COG2076 Membrane transporter of cations and cationic drugs; InterPro IPR000390; KEGG: bur:Bcep18194_A4701 small multidrug resistance protein; PFAM: small multidrug resistance protein; SPTR: Putative mebrane transport protein; PFAM: Small Multidrug Resistance protein.
       0.746
ADR35951.1
Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
   
 
 0.721
ADR35952.1
COGs: COG1622 Heme/copper-type cytochrome/quinol oxidase subunit 2; InterPro IPR002429: IPR003088: IPR009056; KEGG: ttj:TTHA0311 cytochrome caa3 oxidase subunit IIC; PFAM: cytochrome c oxidase subunit II; cytochrome c class I; SPTR: Cytochrome c oxidase subunit 2; PFAM: Cytochrome C oxidase subunit II, periplasmic domain; Cytochrome c.
   
 
 0.721
ADR37030.1
3-Cys thioredoxin peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 0.664
merA
Mercuric reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 0.617
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 0.591
ADR36990.1
Hypothetical protein; InterPro IPR019809; KEGG: msv:Mesil_2367 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.569
rlmN
23S rRNA m(2)A-2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.
       0.552
ADR37433.1
KEGG: msv:Mesil_1663 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.551
ADR37206.1
COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR012999: IPR013027: IPR004099: IPR000815: IPR 006258; KEGG: ttj:TTHA0233 pyruvate dehydrogenase complex, dihydrolipoamide dehydrogenase E3 component; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGR [...]
   
 0.534
Your Current Organism:
Oceanithermus profundus
NCBI taxonomy Id: 670487
Other names: O. profundus DSM 14977, Oceanithermus profundus DSM 14977, Oceanithermus profundus str. DSM 14977, Oceanithermus profundus strain DSM 14977
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