Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADR37448.1Polyphosphate:AMP phosphotransferase; COGs: COG2326 conserved hypothetical protein; InterPro IPR016898: IPR005660; KEGG: dge:Dgeo_2247 hypothetical protein; PFAM: protein of unknown function DUF344; SPTR: Predicted deoxynucleoside kinase; PFAM: Polyphosphate kinase 2 (PPK2); TIGRFAM: polyphosphate:nucleotide phosphotransferase, PPK2 family. (269 aa)    
Predicted Functional Partners:
ADR37281.1
COGs: COG0855 Polyphosphate kinase; InterPro IPR001736: IPR003414; KEGG: msv:Mesil_1242 polyphosphate kinase; PFAM: Polyphosphate kinase; PRIAM: Polyphosphate kinase; SPTR: Polyphosphate kinase; PFAM: Polyphosphate kinase; TIGRFAM: polyphosphate kinase 1.
 
   
 0.770
ADR37282.1
COGs: COG0248 Exopolyphosphatase; InterPro IPR003695: IPR006674; KEGG: msv:Mesil_1243 Ppx/GppA phosphatase; PFAM: Ppx/GppA phosphatase; metal-dependent phosphohydrolase HD sub domain; SPTR: Ppx/GppA phosphatase; PFAM: HD domain; Ppx/GppA phosphatase family; TIGRFAM: exopolyphosphatase.
 
  
 0.663
ADR37447.1
COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR018376: IPR001753; KEGG: mrb:Mrub_1217 enoyl-CoA hydratase/isomerase; PFAM: Enoyl-CoA hydratase/isomerase; SPTR: Enoyl-CoA hydratase/isomerase; PFAM: Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family.
       0.655
ADR37449.1
KEGG: mxa:MXAN_4856 hypothetical protein; SPTR: Putative uncharacterized protein.
  
    0.581
ADR37450.1
KEGG: mxa:MXAN_4856 hypothetical protein; SPTR: Putative uncharacterized protein.
  
    0.567
Your Current Organism:
Oceanithermus profundus
NCBI taxonomy Id: 670487
Other names: O. profundus DSM 14977, Oceanithermus profundus DSM 14977, Oceanithermus profundus str. DSM 14977, Oceanithermus profundus strain DSM 14977
Server load: low (14%) [HD]