Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADR37451.1Short-chain dehydrogenase/reductase SDR; COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002198: IPR002347; KEGG: azl:AZL_d01910 NAD(P)-binding short-chain dehydrogenase/reductase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: NAD(P)-binding short-chain dehydrogenase/reductase; PFAM: short chain dehydrogenase. (263 aa)    
Predicted Functional Partners:
ADR37534.1
Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198: IPR002347; KEGG: pfu:PF1899 putative 2-deoxy-D-gluconate 3-dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Putative 2-deoxy-d-gluconate 3-dehydrogenase; PFAM: short chain dehydrogenase.
  
 
   0.778
ADR36253.1
Short-chain dehydrogenase/reductase SDR; COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002347: IPR002198; KEGG: ttj:TTHA1233 short-chain dehydrogenase/reductase family protein; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenases/reductases family protein; PFAM: short chain dehydrogenase.
  
     0.715
ADR37452.1
COGs: COG1045 Serine acetyltransferase; InterPro IPR001451; KEGG: sat:SYN_01257 serine acetyltransferase; PRIAM: Serine O-acetyltransferase; SPTR: Serine acetyltransferase; TIGRFAM: serine O-acetyltransferase.
  
    0.619
plsY-3
Protein of unknown function DUF205; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
       0.533
ADR37454.1
Small multi-drug export protein; COGs: COG2426 membrane protein; InterPro IPR009577; KEGG: ttj:TTHA0554 small multidrug export protein; PFAM: small multi-drug export protein; SPTR: Hypothetical conserved protein; PFAM: Putative small multi-drug export protein.
       0.424
rplT
LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
       0.424
rpmI
LSU ribosomal protein L35P; InterPro IPR001706: IPR021137; KEGG: msv:Mesil_1252 ribosomal protein L35; PFAM: Ribosomal protein L35; SPTR: Ribosomal protein L35; TIGRFAM: ribosomal protein L35; PFAM: Ribosomal protein L35; TIGRFAM: ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.
       0.421
ADR36388.1
COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR020845: IPR000873; KEGG: ttj:TTHA1463 long-chain-fatty-acid--CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Long-chain-fatty-acid--CoA ligase; PFAM: AMP-binding enzyme.
   
 
 0.409
ADR36389.1
COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR020845: IPR000873; KEGG: ttj:TTHA1430 long-chain fatty acid--CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Long-chain fatty acid--CoA ligase; PFAM: AMP-binding enzyme.
   
 
 0.409
ADR37579.1
COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR020845: IPR000408: IPR000873; KEGG: msv:Mesil_0094 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme.
   
 
 0.409
Your Current Organism:
Oceanithermus profundus
NCBI taxonomy Id: 670487
Other names: O. profundus DSM 14977, Oceanithermus profundus DSM 14977, Oceanithermus profundus str. DSM 14977, Oceanithermus profundus strain DSM 14977
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.