Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADR37463.1Ribosomal large subunit pseudouridine synthase B; COGs: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; InterPro IPR002942: IPR018496: IPR000748: IPR006145; KEGG: ttj:TTHA0219 ribosomal large subunit pseudouridine synthase B; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; SMART: RNA-binding S4 domain protein; SPTR: Pseudouridine synthase; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family. (252 aa)    
Predicted Functional Partners:
cmk
COGs: COG0283 Cytidylate kinase; InterPro IPR011994: IPR003136; KEGG: tth:TTC0089 cytidylate kinase; PFAM: cytidylate kinase region; SPTR: Cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase.
  
 0.946
der
Ribosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
 
  
 0.835
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
 
   
 0.832
ADR36932.1
Exodeoxyribonuclease III Xth; COGs: COG0708 Exonuclease III; InterPro IPR004808: IPR005135: IPR020848: IPR000097; KEGG: abi:Aboo_0823 exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SPTR: Exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III Xth; exodeoxyribonuclease III; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth).
  
    0.831
ADR36268.1
Condensin subunit ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
  
  
 0.607
ADR37464.1
Hypothetical protein; KEGG: ttr:Tter_0222 peptidase M50; SPTR: NnrS family protein.
       0.560
ADR37460.1
KEGG: dra:DR_1218 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.558
ADR37461.1
Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
       0.558
ADR37462.1
FeoA family protein; COGs: COG1918 Fe2+ transport system protein A; InterPro IPR007167; KEGG: acp:A2cp1_3411 FeoA family protein; PFAM: FeoA family protein; SPTR: FeoA family protein; PFAM: FeoA domain.
       0.558
rplT
LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
  
   0.456
Your Current Organism:
Oceanithermus profundus
NCBI taxonomy Id: 670487
Other names: O. profundus DSM 14977, Oceanithermus profundus DSM 14977, Oceanithermus profundus str. DSM 14977, Oceanithermus profundus strain DSM 14977
Server load: low (18%) [HD]