Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADR37469.1KEGG: msv:Mesil_3040 hypothetical protein; SPTR: Putative uncharacterized protein. (173 aa)    
Predicted Functional Partners:
ADR37468.1
COGs: COG4877 conserved hypothetical protein; KEGG: tcu:Tcur_1901 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
ADR37470.1
Phosphoenolpyruvate synthase; InterPro IPR003675; KEGG: tth:TT_P0123 hypothetical protein; PFAM: Abortive infection protein; SPTR: Hypothetical membrane spanning protein; PFAM: CAAX amino terminal protease family.
       0.773
ADR37471.1
Hypothetical protein; KEGG: ttu:TERTU_0080 cytochrome c oxidase assembly protein; SPTR: Putative uncharacterized protein.
       0.714
ADR37467.1
Band 7 protein; COGs: COG0330 Membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001107; KEGG: msv:Mesil_0345 band 7 protein; PFAM: band 7 protein; SMART: band 7 protein; SPTR: Band 7 protein; PFAM: SPFH domain / Band 7 family.
       0.476
trpE
Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...]
       0.434
Your Current Organism:
Oceanithermus profundus
NCBI taxonomy Id: 670487
Other names: O. profundus DSM 14977, Oceanithermus profundus DSM 14977, Oceanithermus profundus str. DSM 14977, Oceanithermus profundus strain DSM 14977
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