Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADR37630.1KEGG: msv:Mesil_3344 hypothetical protein; SPTR: Putative uncharacterized protein. (188 aa)    
Predicted Functional Partners:
ADR37631.1
KEGG: chl:Chy400_1184 ABC-type branched-chain amino acid transport systems periplasmic component-like protein; SPTR: ABC-type branched-chain amino acid transport systems periplasmic component-like protein.
       0.678
ADR37691.1
DNA internalization-related competence protein ComEC/Rec2; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004797: IPR004477; KEGG: msv:Mesil_3192 DNA internalization-related competence protein ComEC/Rec2; PFAM: ComEC/Rec2-related protein; SPTR: DNA internalization-related competence protein ComEC/Rec2; TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2.
  
  
 0.571
ADR37632.1
COGs: COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; InterPro IPR001126: IPR017963; KEGG: mrb:Mrub_3025 DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; PRIAM: DNA-directed DNA polymerase; SPTR: DNA-directed DNA polymerase; PFAM: impB/mucB/samB family C-terminal; impB/mucB/samB family; IMS family HHH motif; Belongs to the DNA polymerase type-Y family.
       0.482
ADR37633.1
Putative PAS/PAC sensor protein; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterProIPR000834: IPR000014: IPR003018: IPR003607: IPR 013767: IPR013655: IPR006674: IPR000700; KEGG: tth:TTC0629 HD-hydrolase domain-containing protein; PFAM: metal-dependent phosphohydrolase HD sub domain; PAS fold-3 domain protein; PAS fold domain protein; GAF domain protein; SMART: metal-dependent phosphohydrolase HD region; GAF domain protein; PAS domain containing protein; SPTR: HD-hydrolase domain; TIGRFAM: PAS sensor protein; PFAM: HD domain; PAS fold; [...]
     
 0.401
Your Current Organism:
Oceanithermus profundus
NCBI taxonomy Id: 670487
Other names: O. profundus DSM 14977, Oceanithermus profundus DSM 14977, Oceanithermus profundus str. DSM 14977, Oceanithermus profundus strain DSM 14977
Server load: low (24%) [HD]