STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mtnK-25-methylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. (405 aa)    
Predicted Functional Partners:
mtnA-2
Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
 
 0.998
mtnA
Translation initiation factor, aIF-2BI family; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
 
 0.993
mtnK
5-methylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
  
  
 
0.910
ADR37637.1
Transketolase domain-containing protein; COGs: COG3959 Transketolase N-terminal subunit; InterPro IPR005474; KEGG: tle:Tlet_1682 transketolase domain-containing protein; PFAM: Transketolase domain-containing protein; SPTR: Transketolase domain protein; PFAM: Transketolase, thiamine diphosphate binding domain.
 
     0.825
ADR37636.1
Transketolase central region; COGs: COG3958 Transketolase C-terminal subunit; InterPro IPR005475: IPR005476; KEGG: tle:Tlet_1683 transketolase central region; PFAM: Transketolase central region; Transketolase domain-containing protein; SPTR: Transketolase central region; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.
 
     0.815
ADR37635.1
COGs: COG1850 Ribulose 1 5-bisphosphate carboxylase large subunit; InterPro IPR000685; KEGG: tle:Tlet_1684 ribulose-bisphosphate carboxylase; PFAM: ribulose bisphosphate carboxylase large chain; SPTR: RubisCO-like protein; PFAM: Ribulose bisphosphate carboxylase large chain, catalytic domain.
 
  
 0.803
ADR37392.1
Methylthioadenosine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
  
  
 0.663
ADR37634.1
Transcriptional regulator, DeoR family; COGs: COG2390 Transcriptional regulator contains sigma factor-related N-terminal domain; InterPro IPR007324; KEGG: tle:Tlet_1685 DeoR family transcriptional regulator; PFAM: sugar-binding domain-containing protein; SPTR: Transcriptional regulator, DeoR family; PFAM: Sigma-70, region 4; Putative sugar-binding domain.
 
     0.640
ADR36901.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
  
 0.524
Your Current Organism:
Oceanithermus profundus
NCBI taxonomy Id: 670487
Other names: O. profundus DSM 14977, Oceanithermus profundus DSM 14977, Oceanithermus profundus str. DSM 14977, Oceanithermus profundus strain DSM 14977
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.