STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHP71028.1PFAM: HpcH/HpaI aldolase/citrate lyase family. (269 aa)    
Predicted Functional Partners:
EHP70051.1
PFAM: Class II Aldolase and Adducin N-terminal domain; TIGRFAM: L-ribulose-5-phosphate 4-epimerase.
  
  
 0.988
EHP71011.1
PFAM: lactate/malate dehydrogenase, alpha/beta C-terminal domain; lactate/malate dehydrogenase, NAD binding domain; Belongs to the LDH/MDH superfamily.
  
 
 0.930
EHP70483.1
Putative acyl-CoA transferase/carnitine dehydratase; PFAM: CoA-transferase family III.
  
 
 0.929
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.919
EHP71292.1
PFAM: Fumarase C-terminus; TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta region.
  
 
 0.917
EHP71293.1
PFAM: Fumarate hydratase (Fumerase); TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha region.
    
 0.917
EHP68101.1
acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta); PFAM: Carboxyl transferase domain.
  
 
 0.917
EHP68270.1
PFAM: CoA-ligase; ATP-grasp domain; TIGRFAM: succinyl-CoA synthetase, beta subunit.
    
 0.917
EHP69329.1
acetyl/propionyl-CoA carboxylase, alpha subunit; PFAM: Biotin-requiring enzyme; overlaps another CDS with the same product name.
  
 
 0.908
EHP69169.1
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
    
 0.901
Your Current Organism:
Metallosphaera yellowstonensis
NCBI taxonomy Id: 671065
Other names: M. yellowstonensis MK1, Metallosphaera sp. MK1, Metallosphaera yellowstonensis MK1, Metallosphaera yellowstonensis str. MK1, Metallosphaera yellowstonensis strain MK1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.