node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EHP68388.1 | EHP68458.1 | MetMK1DRAFT_00028200 | MetMK1DRAFT_00028920 | DNA-directed RNA polymerase, subunit K/omega; PFAM: RNA polymerase Rpb6. | DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit. | 0.899 |
EHP68388.1 | EHP68817.1 | MetMK1DRAFT_00028200 | MetMK1DRAFT_00032630 | DNA-directed RNA polymerase, subunit K/omega; PFAM: RNA polymerase Rpb6. | DNA helicase, Rad3; PFAM: DEAD_2. | 0.956 |
EHP68388.1 | EHP69537.1 | MetMK1DRAFT_00028200 | MetMK1DRAFT_00023040 | DNA-directed RNA polymerase, subunit K/omega; PFAM: RNA polymerase Rpb6. | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
EHP68388.1 | rpoD | MetMK1DRAFT_00028200 | MetMK1DRAFT_00029920 | DNA-directed RNA polymerase, subunit K/omega; PFAM: RNA polymerase Rpb6. | DNA-directed RNA polymerase, alpha subunit/40 kD subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
EHP68388.1 | rpoH | MetMK1DRAFT_00028200 | MetMK1DRAFT_00023030 | DNA-directed RNA polymerase, subunit K/omega; PFAM: RNA polymerase Rpb6. | DNA-directed RNA polymerase, subunit H, RpoH/RPB5; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | 0.999 |
EHP68388.1 | rpoP | MetMK1DRAFT_00028200 | MetMK1DRAFT_00023730 | DNA-directed RNA polymerase, subunit K/omega; PFAM: RNA polymerase Rpb6. | DNA-directed RNA polymerase, subunit RPC10 (contains C4-type Zn-finger); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family. | 0.999 |
EHP68388.1 | tbp | MetMK1DRAFT_00028200 | MetMK1DRAFT_00028860 | DNA-directed RNA polymerase, subunit K/omega; PFAM: RNA polymerase Rpb6. | TATA-box binding protein (TBP), component of TFIID and TFIIIB; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. | 0.974 |
EHP68388.1 | tfe | MetMK1DRAFT_00028200 | MetMK1DRAFT_00022330 | DNA-directed RNA polymerase, subunit K/omega; PFAM: RNA polymerase Rpb6. | TIGR00373 family protein; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seem [...] | 0.981 |
EHP68458.1 | EHP68388.1 | MetMK1DRAFT_00028920 | MetMK1DRAFT_00028200 | DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit. | DNA-directed RNA polymerase, subunit K/omega; PFAM: RNA polymerase Rpb6. | 0.899 |
EHP68458.1 | EHP68817.1 | MetMK1DRAFT_00028920 | MetMK1DRAFT_00032630 | DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit. | DNA helicase, Rad3; PFAM: DEAD_2. | 0.926 |
EHP68458.1 | EHP69537.1 | MetMK1DRAFT_00028920 | MetMK1DRAFT_00023040 | DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit. | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.913 |
EHP68458.1 | EHP70563.1 | MetMK1DRAFT_00028920 | MetMK1DRAFT_00010660 | DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit. | PFAM: Protein of unknown function (DUF790). | 0.937 |
EHP68458.1 | fen | MetMK1DRAFT_00028920 | MetMK1DRAFT_00020610 | DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit. | Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...] | 0.909 |
EHP68458.1 | rpoD | MetMK1DRAFT_00028920 | MetMK1DRAFT_00029920 | DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit. | DNA-directed RNA polymerase, alpha subunit/40 kD subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.912 |
EHP68458.1 | rpoH | MetMK1DRAFT_00028920 | MetMK1DRAFT_00023030 | DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit. | DNA-directed RNA polymerase, subunit H, RpoH/RPB5; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | 0.911 |
EHP68458.1 | rpoP | MetMK1DRAFT_00028920 | MetMK1DRAFT_00023730 | DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit. | DNA-directed RNA polymerase, subunit RPC10 (contains C4-type Zn-finger); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family. | 0.898 |
EHP68458.1 | tbp | MetMK1DRAFT_00028920 | MetMK1DRAFT_00028860 | DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit. | TATA-box binding protein (TBP), component of TFIID and TFIIIB; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. | 0.915 |
EHP68458.1 | tfe | MetMK1DRAFT_00028920 | MetMK1DRAFT_00022330 | DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit. | TIGR00373 family protein; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seem [...] | 0.924 |
EHP68817.1 | EHP68388.1 | MetMK1DRAFT_00032630 | MetMK1DRAFT_00028200 | DNA helicase, Rad3; PFAM: DEAD_2. | DNA-directed RNA polymerase, subunit K/omega; PFAM: RNA polymerase Rpb6. | 0.956 |
EHP68817.1 | EHP68458.1 | MetMK1DRAFT_00032630 | MetMK1DRAFT_00028920 | DNA helicase, Rad3; PFAM: DEAD_2. | DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit. | 0.926 |