STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cbbLRibulose bisphosphate carboxylase large chain (RuBisCO large subunit); RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site. Belongs to the RuBisCO large chain family. Type I subfamily. (476 aa)    
Predicted Functional Partners:
cbbS
Ribulose bisphosphate carboxylase small chain.
 
 0.995
ccmM
Carbon dioxide concentrating mechanism protein CcmM.
  
 0.990
rca
Ribulose bisphosphate carboxylase/oxygenase activase.
  
 0.959
rbcX
RbcX.
   
 
 0.931
mtnX
2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphatephosphatase.
  
 
 0.923
CUR31998.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
    
   0.879
mtnD
Acireductone dioxygenase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
  
  
 0.826
prk
Phosphoribulokinase.
 
  
 0.802
cbbYP
Protein CbbY, plasmid.
 
  
  0.800
mtnB
Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily.
  
 
 0.774
Your Current Organism:
Planktothrix tepida
NCBI taxonomy Id: 671072
Other names: Oscillatoria sp. 4d.1, Oscillatoria sp. PCC 9214, P. tepida PCC 9214, Planktothrix sp. PCC 9214, Planktothrix tepida NIES-2870, Planktothrix tepida PCC 9214
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