STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lntApolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (538 aa)    
Predicted Functional Partners:
CUR31936.1
Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.683
CUR30365.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.655
CUR34551.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.611
CUR33465.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.573
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
     
 0.513
lpxD
UDP-3-O-acylglucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
 
   
 0.499
CUR36072.1
Putative Histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.496
CUR36073.1
Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function.
       0.496
CUR36074.1
Putative Histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.496
CUR36075.1
Histidine kinase.
       0.496
Your Current Organism:
Planktothrix tepida
NCBI taxonomy Id: 671072
Other names: Oscillatoria sp. 4d.1, Oscillatoria sp. PCC 9214, P. tepida PCC 9214, Planktothrix sp. PCC 9214, Planktothrix tepida NIES-2870, Planktothrix tepida PCC 9214
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.