STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gltBGlutamate synthase [NADPH] large chain (NADPH-GOGAT); Function of strongly homologous gene; enzyme. (1529 aa)    
Predicted Functional Partners:
DAMO_0766
FAD-dependent pyridine nucleotide-disulphide oxidoreductase precursor.
 
 0.999
gltD
Glutamate synthase [NADPH] small chain, (NADPH-GOGAT); Function of strongly homologous gene; enzyme.
 0.999
DAMO_2587
Glutamate synthase (NADPH).
 
 0.999
gdh
Glutamate dehydrogenase (NAD(P)+) oxidoreductase protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.998
glnA-2
Glutamine synthetase, type I, N-terminal (Glutamate--ammonia ligase I) (GSI); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the glutamine synthetase family.
  
 
 0.991
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.986
carB
Carbamoyl phosphate synthase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarB family.
  
 
 0.967
glmS
L-glutamine:D-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
   
 0.950
aatA
Aspartate aminotransferase A (AspAT); Function of strongly homologous gene; enzyme.
  
 
 0.948
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
    
 0.948
Your Current Organism:
Methylomirabilis oxyfera
NCBI taxonomy Id: 671143
Other names: C. Methylomirabilis oxyfera, Candidatus Methylomirabilis oxyfera
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