STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (325 aa)    
Predicted Functional Partners:
pdhA
Similar to pyruvate dehydrogenase (Lipoamide) E1 component alpha chain.
 0.999
lpD
Dihydrolipoyl dehydrogenase; Function of strongly homologous gene; enzyme.
 0.999
pdhC
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 0.999
pdhA-2
Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.999
sucB
Similar to 2-oxoglutarate dehydrogenase complex E2 component.
 0.995
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.944
korA
2-oxoglutarate ferredoxin oxidoreductase alpha subunit.
  
 
 0.941
DAMO_0980
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
   
 
 0.935
DAMO_2499
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); Function of strongly homologous gene; enzyme.
   
 
 0.924
DAMO_0981
Thiamine pyrophosphate enzyme domain protein TPP-binding.
     
 0.916
Your Current Organism:
Methylomirabilis oxyfera
NCBI taxonomy Id: 671143
Other names: C. Methylomirabilis oxyfera, Candidatus Methylomirabilis oxyfera
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