STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DAMO_1985Thioredoxin peroxidase (AhpC, Alkyl hydroperoxide reductase); Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (202 aa)    
Predicted Functional Partners:
trxB
Thioredoxin reductase, FAD/NAD(P)-binding; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.714
DAMO_2208
Putative oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 
 0.714
DAMO_1986
Protein of unknown function; No homology to any previously reported sequences.
       0.701
DAMO_1987
Homologs of previously reported genes of unknown function.
  
    0.632
trxA
Fragment of Anthranilate synthase [Includes: Glutamine amidotransferase] (part 1); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thioredoxin family.
  
 
 0.565
guaB
Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 0.532
grpE
Protein grpE (HSP-70 cofactor); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...]
   
 
 0.522
actP
Copper-transporting P-type ATPase; Function of homologous gene experimentally demonstrated in an other organism; transporter.
  
  
 0.507
DAMO_0395
Superoxide dismutase.
  
  
 0.494
DAMO_1984
Membrane protein of unknown function; No homology to any previously reported sequences.
       0.461
Your Current Organism:
Methylomirabilis oxyfera
NCBI taxonomy Id: 671143
Other names: C. Methylomirabilis oxyfera, Candidatus Methylomirabilis oxyfera
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