node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DAMO_0218 | DAMO_1790 | DAMO_0218 | DAMO_1790 | UDP-glucose/GDP-mannose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | Homologs of previously reported genes of unknown function. | 0.922 |
DAMO_0218 | glmU | DAMO_0218 | DAMO_1990 | UDP-glucose/GDP-mannose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | Bifunctional: N-acetyl glucosamine-1-phosphate uridyltransferase (N-terminal); Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.929 |
DAMO_0218 | lpxA | DAMO_0218 | DAMO_1649 | UDP-glucose/GDP-mannose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.828 |
DAMO_0218 | murA | DAMO_0218 | DAMO_2247 | UDP-glucose/GDP-mannose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.907 |
DAMO_0939 | murA | DAMO_0939 | DAMO_2247 | Nucleotidyl transferase. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.801 |
DAMO_0939 | murB | DAMO_0939 | DAMO_2295 | Nucleotidyl transferase. | UDP-N-acetylenolpyruvoylglucosamine reductase (MurB-like); Cell wall formation. | 0.900 |
DAMO_0939 | murC | DAMO_0939 | DAMO_2296 | Nucleotidyl transferase. | UDP-N-acetyl-muramate:alanine ligase, L-alanine adding enzyme; Cell wall formation; Belongs to the MurCDEF family. | 0.800 |
DAMO_1790 | DAMO_0218 | DAMO_1790 | DAMO_0218 | Homologs of previously reported genes of unknown function. | UDP-glucose/GDP-mannose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | 0.922 |
DAMO_1790 | glmU | DAMO_1790 | DAMO_1990 | Homologs of previously reported genes of unknown function. | Bifunctional: N-acetyl glucosamine-1-phosphate uridyltransferase (N-terminal); Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.915 |
DAMO_1790 | lpxA | DAMO_1790 | DAMO_1649 | Homologs of previously reported genes of unknown function. | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.811 |
DAMO_1790 | murA | DAMO_1790 | DAMO_2247 | Homologs of previously reported genes of unknown function. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.906 |
glmU | DAMO_0218 | DAMO_1990 | DAMO_0218 | Bifunctional: N-acetyl glucosamine-1-phosphate uridyltransferase (N-terminal); Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | UDP-glucose/GDP-mannose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | 0.929 |
glmU | DAMO_1790 | DAMO_1990 | DAMO_1790 | Bifunctional: N-acetyl glucosamine-1-phosphate uridyltransferase (N-terminal); Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | Homologs of previously reported genes of unknown function. | 0.915 |
glmU | lpxA | DAMO_1990 | DAMO_1649 | Bifunctional: N-acetyl glucosamine-1-phosphate uridyltransferase (N-terminal); Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.851 |
glmU | murA | DAMO_1990 | DAMO_2247 | Bifunctional: N-acetyl glucosamine-1-phosphate uridyltransferase (N-terminal); Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.943 |
glmU | murC | DAMO_1990 | DAMO_2296 | Bifunctional: N-acetyl glucosamine-1-phosphate uridyltransferase (N-terminal); Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | UDP-N-acetyl-muramate:alanine ligase, L-alanine adding enzyme; Cell wall formation; Belongs to the MurCDEF family. | 0.926 |
lpxA | DAMO_0218 | DAMO_1649 | DAMO_0218 | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | UDP-glucose/GDP-mannose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | 0.828 |
lpxA | DAMO_1790 | DAMO_1649 | DAMO_1790 | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Homologs of previously reported genes of unknown function. | 0.811 |
lpxA | glmU | DAMO_1649 | DAMO_1990 | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Bifunctional: N-acetyl glucosamine-1-phosphate uridyltransferase (N-terminal); Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.851 |
lpxA | murA | DAMO_1649 | DAMO_2247 | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.870 |