node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DAMO_0898 | DAMO_1584 | DAMO_0898 | DAMO_1584 | 4-hydroxybenzoate polyprenyltransferase-related protein; Belongs to the UbiA prenyltransferase family. | Radical SAM domain protein. | 0.817 |
DAMO_0898 | ThiH | DAMO_0898 | DAMO_1578 | 4-hydroxybenzoate polyprenyltransferase-related protein; Belongs to the UbiA prenyltransferase family. | Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.817 |
DAMO_0898 | mqnA | DAMO_0898 | DAMO_2574 | 4-hydroxybenzoate polyprenyltransferase-related protein; Belongs to the UbiA prenyltransferase family. | Conserved protein of unknown function; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.833 |
DAMO_0898 | mqnD | DAMO_0898 | DAMO_2122 | 4-hydroxybenzoate polyprenyltransferase-related protein; Belongs to the UbiA prenyltransferase family. | Conserved protein of unknown function; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. | 0.810 |
DAMO_1584 | DAMO_0898 | DAMO_1584 | DAMO_0898 | Radical SAM domain protein. | 4-hydroxybenzoate polyprenyltransferase-related protein; Belongs to the UbiA prenyltransferase family. | 0.817 |
DAMO_1584 | mqnA | DAMO_1584 | DAMO_2574 | Radical SAM domain protein. | Conserved protein of unknown function; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.982 |
DAMO_1584 | mqnD | DAMO_1584 | DAMO_2122 | Radical SAM domain protein. | Conserved protein of unknown function; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. | 0.819 |
ThiH | DAMO_0898 | DAMO_1578 | DAMO_0898 | Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | 4-hydroxybenzoate polyprenyltransferase-related protein; Belongs to the UbiA prenyltransferase family. | 0.817 |
ThiH | mqnA | DAMO_1578 | DAMO_2574 | Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | Conserved protein of unknown function; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.929 |
ThiH | mqnD | DAMO_1578 | DAMO_2122 | Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | Conserved protein of unknown function; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. | 0.981 |
aatA | hisC | DAMO_1388 | DAMO_1203 | Aspartate aminotransferase A (AspAT); Function of strongly homologous gene; enzyme. | Histidinol-phosphate aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.824 |
aatA | hisC-2 | DAMO_1388 | DAMO_2244 | Aspartate aminotransferase A (AspAT); Function of strongly homologous gene; enzyme. | Histidinol-phosphate aminotransferase 2 (Imidazole acetol-phosphate transaminase 2); Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.844 |
aatA | mqnA | DAMO_1388 | DAMO_2574 | Aspartate aminotransferase A (AspAT); Function of strongly homologous gene; enzyme. | Conserved protein of unknown function; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.800 |
aatA | pheA | DAMO_1388 | DAMO_1202 | Aspartate aminotransferase A (AspAT); Function of strongly homologous gene; enzyme. | P-protein [Includes: Chorismate mutase (CM); Prephenate dehydratase (PDT)]. | 0.992 |
aatA | tyrC | DAMO_1388 | DAMO_1205 | Aspartate aminotransferase A (AspAT); Function of strongly homologous gene; enzyme. | Protein tyrC: Cyclohexadienyl dehydrogenase (Arogenate dehydrogenase) (ADH); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.916 |
aroC | hisC | DAMO_1404 | DAMO_1203 | Fragment of bifunctional: shikimate kinase (N-terminal); Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Histidinol-phosphate aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.682 |
aroC | hisC-2 | DAMO_1404 | DAMO_2244 | Fragment of bifunctional: shikimate kinase (N-terminal); Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Histidinol-phosphate aminotransferase 2 (Imidazole acetol-phosphate transaminase 2); Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.641 |
aroC | mqnA | DAMO_1404 | DAMO_2574 | Fragment of bifunctional: shikimate kinase (N-terminal); Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Conserved protein of unknown function; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.821 |
aroC | pheA | DAMO_1404 | DAMO_1202 | Fragment of bifunctional: shikimate kinase (N-terminal); Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | P-protein [Includes: Chorismate mutase (CM); Prephenate dehydratase (PDT)]. | 0.991 |
aroC | tyrC | DAMO_1404 | DAMO_1205 | Fragment of bifunctional: shikimate kinase (N-terminal); Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Protein tyrC: Cyclohexadienyl dehydrogenase (Arogenate dehydrogenase) (ADH); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.895 |