Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hycDSimilar to membrane-bound [NiFe]-hydrogenase-3, subunit D. (314 aa)    
Predicted Functional Partners:
DAMO_2832
Hydrogenase, large subunit-like protein (HycE-like).
 
 
 0.999
hycG
HycG protein.
 
 
 0.995
DAMO_2828
Homologs of previously reported genes of unknown function.
 
 
 0.991
hyfF
Hydrogenase-4 component F.
 
 
 0.990
DAMO_2830
Homologs of previously reported genes of unknown function.
 
  
 0.976
DAMO_0766
FAD-dependent pyridine nucleotide-disulphide oxidoreductase precursor.
  
 
 0.811
nuoI
NADH-quinone oxidoreductase subunit I (NADH dehydrogenase I subunit I) (NDH-1 subunit I); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
 
 0.788
DAMO_1613
Putative 4Fe-4S ferredoxin iron-sulfur binding domain protein precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 
 0.788
fdhA
Formate dehydrogenase, alpha subunit (fdhA2); Function of strongly homologous gene; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
 
 0.509
fdhA-2
Formate dehydrogenase, alpha subunit (fdhA1); Function of strongly homologous gene; enzyme.
  
 
 0.509
Your Current Organism:
Methylomirabilis oxyfera
NCBI taxonomy Id: 671143
Other names: C. Methylomirabilis oxyfera, Candidatus Methylomirabilis oxyfera
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