node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DAMO_1783 | DAMO_2845 | DAMO_1783 | DAMO_2845 | Protein of unknown function; No homology to any previously reported sequences. | Putative tRNA cytidylyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.442 |
DAMO_1783 | guaB | DAMO_1783 | DAMO_2848 | Protein of unknown function; No homology to any previously reported sequences. | Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.590 |
DAMO_1783 | polA | DAMO_1783 | DAMO_2253 | Protein of unknown function; No homology to any previously reported sequences. | DNA polymerase I (POL I); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.565 |
DAMO_2845 | DAMO_1783 | DAMO_2845 | DAMO_1783 | Putative tRNA cytidylyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | Protein of unknown function; No homology to any previously reported sequences. | 0.442 |
DAMO_2845 | DAMO_2846 | DAMO_2845 | DAMO_2846 | Putative tRNA cytidylyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.541 |
DAMO_2845 | dapB | DAMO_2845 | DAMO_2315 | Putative tRNA cytidylyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | Dihydrodipicolinate reductase (DHPR); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.823 |
DAMO_2845 | guaB | DAMO_2845 | DAMO_2848 | Putative tRNA cytidylyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.481 |
DAMO_2845 | metG | DAMO_2845 | DAMO_1159 | Putative tRNA cytidylyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | Methionyl-tRNA synthetase (Methionine--tRNA ligase) (MetRS); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.502 |
DAMO_2845 | pheT | DAMO_2845 | DAMO_1857 | Putative tRNA cytidylyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | Phenylalanyl-tRNA synthetase beta chain (Phenylalanine--tRNA ligase beta chain); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.438 |
DAMO_2845 | pnp | DAMO_2845 | DAMO_0581 | Putative tRNA cytidylyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | Polyribonucleotide nucleotidyltransferase (Polynucleotide phosphorylase) (PNPase); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.511 |
DAMO_2845 | polA | DAMO_2845 | DAMO_2253 | Putative tRNA cytidylyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | DNA polymerase I (POL I); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.431 |
DAMO_2845 | ribD | DAMO_2845 | DAMO_1426 | Putative tRNA cytidylyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | Bifunctional: diaminohydroxyphosphoribosylaminopyrimidine deaminase (N-terminal); Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.531 |
DAMO_2845 | trpS | DAMO_2845 | DAMO_2847 | Putative tRNA cytidylyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | Tryptophanyl-tRNA synthetase (Tryptophan--tRNA ligase) (TrpRS); Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.628 |
DAMO_2846 | DAMO_2845 | DAMO_2846 | DAMO_2845 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Putative tRNA cytidylyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.541 |
DAMO_2846 | guaB | DAMO_2846 | DAMO_2848 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.618 |
DAMO_2846 | trpS | DAMO_2846 | DAMO_2847 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Tryptophanyl-tRNA synthetase (Tryptophan--tRNA ligase) (TrpRS); Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.733 |
dapB | DAMO_2845 | DAMO_2315 | DAMO_2845 | Dihydrodipicolinate reductase (DHPR); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Putative tRNA cytidylyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.823 |
dapB | pheT | DAMO_2315 | DAMO_1857 | Dihydrodipicolinate reductase (DHPR); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Phenylalanyl-tRNA synthetase beta chain (Phenylalanine--tRNA ligase beta chain); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.487 |
dapB | polA | DAMO_2315 | DAMO_2253 | Dihydrodipicolinate reductase (DHPR); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | DNA polymerase I (POL I); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.563 |
guaB | DAMO_1783 | DAMO_2848 | DAMO_1783 | Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Protein of unknown function; No homology to any previously reported sequences. | 0.590 |