STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DAMO_3152Homologs of previously reported genes of unknown function. (140 aa)    
Predicted Functional Partners:
rtcB
Homologs of previously reported genes of unknown function; Belongs to the RtcB family.
 
 0.967
rtcA
Putative RNA 3'-terminal phosphate cyclase (RNA-3'-phosphate cyclase) (RNA cyclase); Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
 
 
 
 0.652
ybbA
Putative transporter subunit: ATP-binding component of ABC superfamily; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
    0.562
DAMO_3153
Homologs of previously reported genes of unknown function.
       0.559
DAMO_3155
Efflux transporter, RND family, MFP subunit precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.559
DAMO_3156
Homologs of previously reported genes of unknown function.
       0.559
DAMO_2617
Conserved protein of unknown function; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.
 
     0.428
DAMO_3157
Exported protein of unknown function; No homology to any previously reported sequences.
       0.402
DAMO_3158
Protein of unknown function; No homology to any previously reported sequences.
       0.402
DAMO_3159
Putative RNA polymerase sigma-H factor (Sigma-30); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the sigma-70 factor family. ECF subfamily.
       0.402
Your Current Organism:
Methylomirabilis oxyfera
NCBI taxonomy Id: 671143
Other names: C. Methylomirabilis oxyfera, Candidatus Methylomirabilis oxyfera
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