STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (403 aa)    
Predicted Functional Partners:
kynA
Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
 
 
 0.999
KUM97041.1
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.985
KUM93067.1
Lipase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.983
KUM93252.1
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.938
KUM91925.1
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.938
KUM95865.1
Catalase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the catalase family.
   
 
 0.891
KUM93079.1
Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.877
KUM97290.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.843
KUM98789.1
Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.756
KUM95366.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.756
Your Current Organism:
Streptomyces cellostaticus
NCBI taxonomy Id: 67285
Other names: ATCC 23894, CBS 680.68, DSM 40189, IFO 12849, ISP 5189, JCM 4183, JCM 4631, NBRC 12849, NCIMB 9830, NRRL-ISP 5189, S. cellostaticus
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