Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yehT_2Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)    
Predicted Functional Partners:
ypdA
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.974
yehU
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.868
AMG30711.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.534
rcsC_4
Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.529
AMG29318.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.520
barA_2
Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.503
rsd
Anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Rsd/AlgQ family.
  
  
 0.458
rseA
Anti-sigma E factor; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degradi [...]
   
  
 0.440
rseB
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.414
barA_1
Hybrid sensor histidine kinase/response regulator; Part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.408
Your Current Organism:
Grimontia hollisae
NCBI taxonomy Id: 673
Other names: ATCC 33564, CAIM 625, CCUG 13625, CDC 0075-80, CIP 101886, DSM 15132, G. hollisae, IMET 12291, LMG 17719, LMG:17719, NCTC 11640, Special Bacteriology group EF-13, Vibrio hollisae
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