Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hnrTwo-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa)    
Predicted Functional Partners:
barA_1
Hybrid sensor histidine kinase/response regulator; Part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.826
barA_4
Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.778
cpxA
Two-component sensor protein; Part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 
 0.755
luxQ
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.751
barA_5
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.736
mprA
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.720
cheY_3
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   0.709
srrA
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.709
torR
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.706
envZ
Osmolarity sensor protein; Membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 
 0.700
Your Current Organism:
Grimontia hollisae
NCBI taxonomy Id: 673
Other names: ATCC 33564, CAIM 625, CCUG 13625, CDC 0075-80, CIP 101886, DSM 15132, G. hollisae, IMET 12291, LMG 17719, LMG:17719, NCTC 11640, Special Bacteriology group EF-13, Vibrio hollisae
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.