STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sixAPhosphohistidine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (164 aa)    
Predicted Functional Partners:
ptrA_2
Peptidase M16; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M16 family.
 
     0.622
yejK
Nucleoid-associated protein NdpA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.597
AMG31377.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.563
rseA
Anti-sigma E factor; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degradi [...]
  
    0.543
fabR
Transcriptional regulator; Negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.540
nlpI
Lipoprotein NlpI; May be involved in cell division.
  
     0.535
nfuA
Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
     0.519
zipA
Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
  
     0.498
rraB
RNase E inhibitor protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
  
     0.481
glpG
Rhomboid family intramembrane serine protease GlpG; Protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.476
Your Current Organism:
Grimontia hollisae
NCBI taxonomy Id: 673
Other names: ATCC 33564, CAIM 625, CCUG 13625, CDC 0075-80, CIP 101886, DSM 15132, G. hollisae, IMET 12291, LMG 17719, LMG:17719, NCTC 11640, Special Bacteriology group EF-13, Vibrio hollisae
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