Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
canCarbonate dehydratase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (215 aa)    
Predicted Functional Partners:
yrdA
Gamma carbonic anhydrase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.841
cbbS1
AAA family ATPase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.817
focA_1
Formate transporter FocA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.815
focA_2
Formate transporter FocA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.800
gpt
Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
   
    0.771
ychM_1
Bicarbonate transporter BicA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.717
panC
Pantoate--beta-alanine ligase; Catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.595
drrA_2
ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.595
guaB_1
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.554
ebgC
beta-D-galactosidase; In Escherichia coli this is the second beta-galactosidase system; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.443
Your Current Organism:
Grimontia hollisae
NCBI taxonomy Id: 673
Other names: ATCC 33564, CAIM 625, CCUG 13625, CDC 0075-80, CIP 101886, DSM 15132, G. hollisae, IMET 12291, LMG 17719, LMG:17719, NCTC 11640, Special Bacteriology group EF-13, Vibrio hollisae
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