| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| infB | pyrH | AL542_12615 | AL542_06095 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.620 |
| infB | rssA_1 | AL542_12615 | AL542_07345 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.661 |
| infB | tsf | AL542_12615 | AL542_06100 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.948 |
| lpxD | pyrH | AL542_06055 | AL542_06095 | UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.719 |
| lpxD | rseP | AL542_06055 | AL542_06070 | UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | Zinc metallopeptidase RseP; Catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.742 |
| lpxD | rssA_1 | AL542_06055 | AL542_07345 | UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.692 |
| lpxD | skp | AL542_06055 | AL542_06060 | UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | Molecular chaperone; Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm. | 0.969 |
| lpxD | tsf | AL542_06055 | AL542_06100 | UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.664 |
| nlpB | rssA_1 | AL542_05750 | AL542_07345 | Outer membrane assembly protein BamC; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.887 |
| nlpB | skp | AL542_05750 | AL542_06060 | Outer membrane assembly protein BamC; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Molecular chaperone; Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm. | 0.445 |
| nlpB | smpA | AL542_05750 | AL542_06400 | Outer membrane assembly protein BamC; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Hypothetical protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.914 |
| nlpB | yfgL | AL542_05750 | AL542_13110 | Outer membrane assembly protein BamC; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Outer membrane protein assembly factor BamB; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.873 |
| nlpB | yfiO | AL542_05750 | AL542_06540 | Outer membrane assembly protein BamC; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Hypothetical protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.964 |
| pyrH | infB | AL542_06095 | AL542_12615 | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.620 |
| pyrH | lpxD | AL542_06095 | AL542_06055 | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.719 |
| pyrH | rseP | AL542_06095 | AL542_06070 | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Zinc metallopeptidase RseP; Catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.663 |
| pyrH | rssA_1 | AL542_06095 | AL542_07345 | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.687 |
| pyrH | skp | AL542_06095 | AL542_06060 | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Molecular chaperone; Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm. | 0.459 |
| pyrH | tsf | AL542_06095 | AL542_06100 | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.970 |
| rseP | lpxD | AL542_06070 | AL542_06055 | Zinc metallopeptidase RseP; Catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.742 |