STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
polC_43'-5' exonuclease of DNA polymerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)    
Predicted Functional Partners:
AMG31355.1
Cyclic nucleotide-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.951
polC_3
DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.925
dnaQ
DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
  
  
  0.919
polC_1
3'-5' exonuclease of DNA polymerase III; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.919
guaB_2
Cyclic nucleotide-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.778
AMG30825.1
Cyclic nucleotide-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.747
dnaN
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.658
betP_1
BCCT transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the BCCT transporter (TC 2.A.15) family.
 
     0.645
dnaE
DNA polymerase III subunit alpha; Catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.641
dnaX
DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 
 0.630
Your Current Organism:
Grimontia hollisae
NCBI taxonomy Id: 673
Other names: ATCC 33564, CAIM 625, CCUG 13625, CDC 0075-80, CIP 101886, DSM 15132, G. hollisae, IMET 12291, LMG 17719, LMG:17719, NCTC 11640, Special Bacteriology group EF-13, Vibrio hollisae
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