| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| crr | gph_2 | AL542_05660 | AL542_14720 | PTS glucose transporter subunit IIA; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the rate-limiting step in dNTP synthesis; frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
| crr | murQ | AL542_05660 | AL542_04120 | PTS glucose transporter subunit IIA; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. | 0.924 |
| gph_2 | crr | AL542_14720 | AL542_05660 | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the rate-limiting step in dNTP synthesis; frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | PTS glucose transporter subunit IIA; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
| gph_2 | moaA | AL542_14720 | AL542_14435 | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the rate-limiting step in dNTP synthesis; frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cyclic pyranopterin phosphate synthase MoaA; Together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.639 |
| gph_2 | murQ | AL542_14720 | AL542_04120 | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the rate-limiting step in dNTP synthesis; frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. | 0.900 |
| gph_2 | purL | AL542_14720 | AL542_05930 | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the rate-limiting step in dNTP synthesis; frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.497 |
| gph_2 | rpe | AL542_14720 | AL542_08355 | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the rate-limiting step in dNTP synthesis; frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribulose phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. | 0.517 |
| gph_2 | ubiG | AL542_14720 | AL542_14725 | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the rate-limiting step in dNTP synthesis; frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional 3-demethylubiquinol 3-O-methyltransferase/2-polyprenyl-6-hydroxyphenol methylase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.719 |
| gph_2 | yqaB_1 | AL542_14720 | AL542_06670 | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the rate-limiting step in dNTP synthesis; frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | 6-phosphogluconate phosphatase; YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.411 |
| moaA | gph_2 | AL542_14435 | AL542_14720 | Cyclic pyranopterin phosphate synthase MoaA; Together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the rate-limiting step in dNTP synthesis; frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.639 |
| murQ | crr | AL542_04120 | AL542_05660 | N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. | PTS glucose transporter subunit IIA; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.924 |
| murQ | gph_2 | AL542_04120 | AL542_14720 | N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the rate-limiting step in dNTP synthesis; frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
| purL | gph_2 | AL542_05930 | AL542_14720 | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the rate-limiting step in dNTP synthesis; frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.497 |
| purL | rpe | AL542_05930 | AL542_08355 | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | Ribulose phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. | 0.421 |
| rpe | gph_2 | AL542_08355 | AL542_14720 | Ribulose phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the rate-limiting step in dNTP synthesis; frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.517 |
| rpe | purL | AL542_08355 | AL542_05930 | Ribulose phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.421 |
| ubiG | gph_2 | AL542_14725 | AL542_14720 | Bifunctional 3-demethylubiquinol 3-O-methyltransferase/2-polyprenyl-6-hydroxyphenol methylase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the rate-limiting step in dNTP synthesis; frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.719 |
| yqaB_1 | gph_2 | AL542_06670 | AL542_14720 | 6-phosphogluconate phosphatase; YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the rate-limiting step in dNTP synthesis; frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.411 |