STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KUN63569.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)    
Predicted Functional Partners:
ftsH
Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
 0.854
arc
Proteasome ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
   
 
 0.586
KUN59880.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0301 (AlgH) family.
  
    0.577
Pip_3
Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.560
KUN71757.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.526
SprD_3
Streptogrisin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.517
KUN68760.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.509
MshD_2
GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.492
KUN71767.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.483
hflX
ATP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
  
  
 0.407
Your Current Organism:
Streptomyces griseorubiginosus
NCBI taxonomy Id: 67304
Other names: ATCC 23627, ATCC 23946 [[Streptomyces phaeopurpureus]], ATCC 23947 [[Streptomyces phaeoviridis]], ATCC 25459, Actinomyces griseorubiginosus, BCRC 12124, BCRC 13754 [[Streptomyces phaeopurpureus]], CBS 692.69, CBS 930.68 [[Streptomyces phaeopurpureus]], CCRC 12124, CCRC 13754 [[Streptomyces phaeopurpureus]], CCRC:12124, CCRC:13754 [[Streptomyces phaeopurpureus]], DSM 40125 [[Streptomyces phaeopurpureus]], DSM 40469, HAMBI 950 [[Streptomyces phaeopurpureus]], IFO 12899 [[Streptomyces phaeopurpureus]], IFO 12900 [[Streptomyces phaeoviridis]], IFO 13047, IFO 3930 [[Streptomyces phaeopurpureus]], INA 7712, ISP 5125 [[Streptomyces phaeopurpureus]], ISP 5469, JCM 4101 [[Streptomyces phaeopurpureus]], JCM 4481, JCM 4660 [[Streptomyces phaeopurpureus]], JCM 4661 [[Streptomyces phaeoviridis]], KCTC 9764 [[Streptomyces phaeopurpureus]], LMG 19941, LMG:19941, NBRC 12899 [[Streptomyces phaeopurpureus]], NBRC 12900 [[Streptomyces phaeoviridis]], NBRC 13047, NBRC 3930 [[Streptomyces phaeopurpureus]], NCIMB 9832 [[Streptomyces phaeoviridis]], NRRL B-12384, NRRL B-2258 [[Streptomyces phaeoviridis]], NRRL B-2260 [[Streptomyces phaeopurpureus]], NRRL-ISP 5125 [[Streptomyces phaeopurpureus]], NRRL-ISP 5469, NRRL:B:2258 [[Streptomyces phaeoviridis]], S. griseorubiginosus, Streptomyces griseirubiginosus, Streptomyces phaeopurpureus, Streptomyces phaeoviridis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.