Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SEB88080.1Na+/melibiose symporter. (452 aa)    
Predicted Functional Partners:
SEB88116.1
Short-chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
    0.803
SEB88156.1
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD.
       0.781
SEE23924.1
Glutamate or tyrosine decarboxylase.
 
     0.773
SEB88197.1
PucR C-terminal helix-turn-helix domain-containing protein.
 
     0.616
SED78289.1
Thymidylate synthase.
    
  0.579
thyX
Thymidylate synthase (FAD); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
     
  0.571
tdk
Thymidine kinase.
     
  0.571
SEC77789.1
Nucleoside diphosphate kinase.
     
  0.497
SEC77901.1
Nucleoside diphosphate kinase.
     
  0.497
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
  0.497
Your Current Organism:
Streptomyces misionensis
NCBI taxonomy Id: 67331
Other names: ATCC 14991, ATCC 25475, BCRC 12094, CBS 885.69, CCRC 12094, CCRC:12094, DSM 40306, IFO 13063, ISP 5306, JCM 4497, NBRC 13063, NRRL B-3230, NRRL-ISP 5306, S. misionensis, Streptomyces misionesensis, VKM Ac-626
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