Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SEB96719.1Uncharacterized conserved protein, DUF2267 family. (128 aa)    
Predicted Functional Partners:
SEB99490.1
Uncharacterized conserved protein, DUF2267 family.
  
     0.712
SEB96755.1
Glyoxylase, beta-lactamase superfamily II.
       0.683
SED01200.1
5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
  
  
  0.613
gcvT
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.
     
  0.553
folD
Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
     
  0.503
folD-2
Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
     
  0.503
SEC73132.1
Dehydrogenase (flavoprotein).
  
     0.493
purN
Formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
     
  0.486
SEC71949.1
Dehydrogenase (flavoprotein).
  
     0.474
SEB96802.1
Mannosyltransferase (PIG-V).
       0.440
Your Current Organism:
Streptomyces misionensis
NCBI taxonomy Id: 67331
Other names: ATCC 14991, ATCC 25475, BCRC 12094, CBS 885.69, CCRC 12094, CCRC:12094, DSM 40306, IFO 13063, ISP 5306, JCM 4497, NBRC 13063, NRRL B-3230, NRRL-ISP 5306, S. misionensis, Streptomyces misionesensis, VKM Ac-626
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