Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SEC08386.1Two-component system, OmpR family, sensor histidine kinase BaeS. (605 aa)    
Predicted Functional Partners:
SED73752.1
Signal transduction histidine kinase.
  
 0.987
SEC08424.1
DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain.
 
  0.976
SED33524.1
Two-component system, OmpR family, response regulator MprA.
 
  0.862
SEE29379.1
DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain.
 
  0.848
SEB96429.1
DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain.
 
  0.846
SED51596.1
DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain; Manually curated.
 
  0.844
SED46938.1
DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain.
 
  0.842
SED74594.1
DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain.
 
  0.841
SED60715.1
Response regulator receiver domain-containing protein.
 
  0.840
SEB95816.1
Two-component system, OmpR family, response regulator; Manually curated.
 
  0.837
Your Current Organism:
Streptomyces misionensis
NCBI taxonomy Id: 67331
Other names: ATCC 14991, ATCC 25475, BCRC 12094, CBS 885.69, CCRC 12094, CCRC:12094, DSM 40306, IFO 13063, ISP 5306, JCM 4497, NBRC 13063, NRRL B-3230, NRRL-ISP 5306, S. misionensis, Streptomyces misionesensis, VKM Ac-626
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