close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEC43801.1Two-component system, OmpR family, sensor kinase. (493 aa)    
Predicted Functional Partners:
SED73752.1
Signal transduction histidine kinase.
  
0.999
SEC43834.1
Two-component system, OmpR family, response regulator.
 
 0.979
SED21236.1
Two-component system, OmpR family, response regulator.
 
 0.914
SEB95816.1
Two-component system, OmpR family, response regulator; Manually curated.
 
 0.902
SEC08424.1
DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain.
 
 0.882
SEB96429.1
DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain.
 
 0.879
SED33524.1
Two-component system, OmpR family, response regulator MprA.
 
 0.879
SED25011.1
Two-component system, OmpR family, response regulator MprA.
 
 0.875
SED33781.1
Two-component system, OmpR family, response regulator MprA.
 
 0.875
SEC95694.1
Two-component system, OmpR family, response regulator MtrA.
 
 0.873
Your Current Organism:
Streptomyces misionensis
NCBI taxonomy Id: 67331
Other names: ATCC 14991, ATCC 25475, BCRC 12094, CBS 885.69, CCRC 12094, CCRC:12094, DSM 40306, IFO 13063, ISP 5306, JCM 4497, NBRC 13063, NRRL B-3230, NRRL-ISP 5306, S. misionensis, Streptomyces misionesensis, VKM Ac-626
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