Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SEC47496.1DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains. (223 aa)    
Predicted Functional Partners:
SED73752.1
Signal transduction histidine kinase.
   
 0.959
SED30058.1
Signal transduction histidine kinase.
  
 0.881
SEC53648.1
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
  0.864
SEC47454.1
Putative RecB family exonuclease.
       0.863
SEC67135.1
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
  
  0.853
SED49890.1
Signal transduction histidine kinase.
  
  0.848
SED76346.1
Signal transduction histidine kinase.
  
  0.847
SED64691.1
Signal transduction histidine kinase.
  
  0.844
SED11075.1
Signal transduction histidine kinase.
  
  0.841
SED11007.1
Signal transduction histidine kinase.
  
  0.837
Your Current Organism:
Streptomyces misionensis
NCBI taxonomy Id: 67331
Other names: ATCC 14991, ATCC 25475, BCRC 12094, CBS 885.69, CCRC 12094, CCRC:12094, DSM 40306, IFO 13063, ISP 5306, JCM 4497, NBRC 13063, NRRL B-3230, NRRL-ISP 5306, S. misionensis, Streptomyces misionesensis, VKM Ac-626
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