Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SEC48518.1Phosphoribosyl transferase domain-containing protein. (425 aa)    
Predicted Functional Partners:
SEC48474.1
Poly-gamma-glutamate synthesis protein (capsule biosynthesis protein).
 
    0.886
SEC48557.1
Protein of unknown function.
 
     0.824
SEC48598.1
SEC-C motif-containing protein; Manually curated; Belongs to the UPF0225 family.
       0.576
pyrD
Dihydroorotate oxidase A; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
 
  
  0.548
SEC48395.1
DNA polymerase (family 10).
 
     0.543
SEB96669.1
Dienelactone hydrolase.
       0.537
pyrF
Orotidine-5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
     
 0.505
SED07543.1
Tagatose 6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family.
  
  
 0.411
SEE29738.1
Fructose-1-phosphate kinase; Belongs to the carbohydrate kinase PfkB family.
  
  
 0.411
SEC50464.1
Uncharacterized conserved protein YecE, DUF72 family.
 
     0.402
Your Current Organism:
Streptomyces misionensis
NCBI taxonomy Id: 67331
Other names: ATCC 14991, ATCC 25475, BCRC 12094, CBS 885.69, CCRC 12094, CCRC:12094, DSM 40306, IFO 13063, ISP 5306, JCM 4497, NBRC 13063, NRRL B-3230, NRRL-ISP 5306, S. misionensis, Streptomyces misionesensis, VKM Ac-626
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