Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SEC70344.1Subtilase family protein. (651 aa)    
Predicted Functional Partners:
SEC70264.1
Protein of unknown function.
       0.722
SEC70301.1
Uncharacterized conserved protein, DUF305 family.
       0.722
SEC70216.1
Transcriptional regulator, BadM/Rrf2 family.
       0.668
SEB94293.1
Phospholipase C.
  
     0.561
leuS
leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.537
nadE
NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
       0.537
SED39105.1
Hypothetical protein.
  
     0.521
SED59445.1
Dual specificity phosphatase, catalytic domain.
  
     0.512
SEE18743.1
Chitinase.
  
     0.459
SED72923.1
Serine protease, S1-C subfamily, contains C-terminal PDZ domain.
  
     0.440
Your Current Organism:
Streptomyces misionensis
NCBI taxonomy Id: 67331
Other names: ATCC 14991, ATCC 25475, BCRC 12094, CBS 885.69, CCRC 12094, CCRC:12094, DSM 40306, IFO 13063, ISP 5306, JCM 4497, NBRC 13063, NRRL B-3230, NRRL-ISP 5306, S. misionensis, Streptomyces misionesensis, VKM Ac-626
Server load: medium (62%) [HD]