| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SEC32297.1 | SEC46176.1 | SAMN04490357_1720 | SAMN04490357_2058 | Exonuclease SbcC. | 5'-3' exonuclease. | 0.832 |
| SEC32297.1 | SED17788.1 | SAMN04490357_1720 | SAMN04490357_4043 | Exonuclease SbcC. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.441 |
| SEC32297.1 | SED43380.1 | SAMN04490357_1720 | SAMN04490357_4795 | Exonuclease SbcC. | ATP-dependent DNA helicase PcrA. | 0.625 |
| SEC32297.1 | SED46544.1 | SAMN04490357_1720 | SAMN04490357_4882 | Exonuclease SbcC. | DNA polymerase-3 subunit beta. | 0.441 |
| SEC32297.1 | SED55580.1 | SAMN04490357_1720 | SAMN04490357_5140 | Exonuclease SbcC. | UvrD-like helicase C-terminal domain-containing protein; Belongs to the helicase family. UvrD subfamily. | 0.645 |
| SEC32297.1 | SED55616.1 | SAMN04490357_1720 | SAMN04490357_5141 | Exonuclease SbcC. | DNA helicase-2 / ATP-dependent DNA helicase PcrA; Belongs to the helicase family. UvrD subfamily. | 0.592 |
| SEC32297.1 | SED55769.1 | SAMN04490357_1720 | SAMN04490357_5145 | Exonuclease SbcC. | ATP-dependent DNA helicase, Rep family. | 0.947 |
| SEC32297.1 | polA | SAMN04490357_1720 | SAMN04490357_2428 | Exonuclease SbcC. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.871 |
| SEC32297.1 | recA | SAMN04490357_1720 | SAMN04490357_5688 | Exonuclease SbcC. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.869 |
| SEC32297.1 | topA | SAMN04490357_1720 | SAMN04490357_4386 | Exonuclease SbcC. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.878 |
| SEC46176.1 | SEC32297.1 | SAMN04490357_2058 | SAMN04490357_1720 | 5'-3' exonuclease. | Exonuclease SbcC. | 0.832 |
| SEC46176.1 | SED17788.1 | SAMN04490357_2058 | SAMN04490357_4043 | 5'-3' exonuclease. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.902 |
| SEC46176.1 | SED43380.1 | SAMN04490357_2058 | SAMN04490357_4795 | 5'-3' exonuclease. | ATP-dependent DNA helicase PcrA. | 0.619 |
| SEC46176.1 | SED46544.1 | SAMN04490357_2058 | SAMN04490357_4882 | 5'-3' exonuclease. | DNA polymerase-3 subunit beta. | 0.902 |
| SEC46176.1 | SED55580.1 | SAMN04490357_2058 | SAMN04490357_5140 | 5'-3' exonuclease. | UvrD-like helicase C-terminal domain-containing protein; Belongs to the helicase family. UvrD subfamily. | 0.668 |
| SEC46176.1 | SED55616.1 | SAMN04490357_2058 | SAMN04490357_5141 | 5'-3' exonuclease. | DNA helicase-2 / ATP-dependent DNA helicase PcrA; Belongs to the helicase family. UvrD subfamily. | 0.605 |
| SEC46176.1 | SED55769.1 | SAMN04490357_2058 | SAMN04490357_5145 | 5'-3' exonuclease. | ATP-dependent DNA helicase, Rep family. | 0.951 |
| SEC46176.1 | polA | SAMN04490357_2058 | SAMN04490357_2428 | 5'-3' exonuclease. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.455 |
| SEC46176.1 | recA | SAMN04490357_2058 | SAMN04490357_5688 | 5'-3' exonuclease. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.910 |
| SEC46176.1 | topA | SAMN04490357_2058 | SAMN04490357_4386 | 5'-3' exonuclease. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.717 |
