STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SAMN05216505_104151Uncharacterized protein. (79 aa)    
Predicted Functional Partners:
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
    
 0.632
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
  0.594
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
    
  0.590
SAMN05216505_11390
Acyl transferase domain-containing protein.
  
 
 0.578
SAMN05216505_11391
Amino acid adenylation domain-containing protein.
  
 
 0.578
SAMN05216505_101944
Glutamate synthase (NADPH/NADH) large chain.
     
 0.551
SAMN05216505_104314
PTS system, fructose-specific IIC component.
  
 
 0.543
SAMN05216505_1085
Histidine kinase.
     
 0.537
SAMN05216505_10848
Vitamin B12-dependent ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
    
  0.528
SAMN05216505_11048
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
    
  0.528
Your Current Organism:
Streptomyces prasinopilosus
NCBI taxonomy Id: 67344
Other names: ATCC 19799, BCRC 13678, CBS 551.68, CCRC 13678, CCRC:13678, CGMCC 4.3504 [[Streptomyces emeiensis]], DSM 40098, DSM 41884 [[Streptomyces emeiensis]], IFO 12809, ISP 5098, JCM 15479 [[Streptomyces emeiensis]], JCM 4207, JCM 4404, LMG 19345, LMG:19345, NBRC 12809, NCIMB 9842, NRRL B-2711, NRRL-ISP 5098, S. prasinopilosus, Streptomyces emeiensis, Streptomyces emeiensis Sun et al. 2007, Streptomyces sp. 034776, UNIQEM 185, strain 4776 [[Streptomyces emeiensis]]
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