STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (375 aa)    
Predicted Functional Partners:
SAMN05216505_102123
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
 
 
 0.998
SAMN05216505_102124
Chlorite dismutase.
 
 0.990
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.977
SAMN05216505_1011124
Magnesium chelatase subunit D.
  
 
 0.943
SAMN05216505_101719
Heme oxygenase.
 
  
 0.931
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
   
 
 0.921
SAMN05216505_101854
Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.
     
 0.919
SAMN05216505_1133
annotation not available
   
 
 0.918
SAMN05216505_101783
Phytoene dehydrogenase-related protein.
  
 
 0.895
SAMN05216505_108113
Inositol-1-monophosphatase; Belongs to the inositol monophosphatase superfamily.
       0.874
Your Current Organism:
Streptomyces prasinopilosus
NCBI taxonomy Id: 67344
Other names: ATCC 19799, BCRC 13678, CBS 551.68, CCRC 13678, CCRC:13678, CGMCC 4.3504 [[Streptomyces emeiensis]], DSM 40098, DSM 41884 [[Streptomyces emeiensis]], IFO 12809, ISP 5098, JCM 15479 [[Streptomyces emeiensis]], JCM 4207, JCM 4404, LMG 19345, LMG:19345, NBRC 12809, NCIMB 9842, NRRL B-2711, NRRL-ISP 5098, S. prasinopilosus, Streptomyces emeiensis, Streptomyces emeiensis Sun et al. 2007, Streptomyces sp. 034776, UNIQEM 185, strain 4776 [[Streptomyces emeiensis]]
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