STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkA-2ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (341 aa)    
Predicted Functional Partners:
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.980
SAMN05216505_110215
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 
 0.942
SAMN05216505_101951
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 
 0.922
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
  
 0.920
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
  
 0.908
SAMN05216505_10924
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
 
 
 0.901
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
   
  
 0.874
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
  
 
 0.864
SAMN05216505_103137
Fructose-1,6-bisphosphatase.
   
 
 0.855
SAMN05216505_102562
Fructose-bisphosphate aldolase, class II.
 
 
 0.849
Your Current Organism:
Streptomyces prasinopilosus
NCBI taxonomy Id: 67344
Other names: ATCC 19799, BCRC 13678, CBS 551.68, CCRC 13678, CCRC:13678, CGMCC 4.3504 [[Streptomyces emeiensis]], DSM 40098, DSM 41884 [[Streptomyces emeiensis]], IFO 12809, ISP 5098, JCM 15479 [[Streptomyces emeiensis]], JCM 4207, JCM 4404, LMG 19345, LMG:19345, NBRC 12809, NCIMB 9842, NRRL B-2711, NRRL-ISP 5098, S. prasinopilosus, Streptomyces emeiensis, Streptomyces emeiensis Sun et al. 2007, Streptomyces sp. 034776, UNIQEM 185, strain 4776 [[Streptomyces emeiensis]]
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