node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEO38678.1 | SEO42026.1 | SAMN05660991_00052 | SAMN05660991_00220 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone DnaK (HSP70); Belongs to the heat shock protein 70 family. | 0.620 |
SEO38678.1 | SEP09018.1 | SAMN05660991_00052 | SAMN05660991_03188 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | 0.816 |
SEO38678.1 | SEP19122.1 | SAMN05660991_00052 | SAMN05660991_03785 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | Hypothetical chaperone protein. | 0.620 |
SEO38678.1 | dnaJ | SAMN05660991_00052 | SAMN05660991_00846 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.544 |
SEO38678.1 | dnaJ-2 | SAMN05660991_00052 | SAMN05660991_02869 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.544 |
SEO38678.1 | dnaK | SAMN05660991_00052 | SAMN05660991_02867 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.620 |
SEO38678.1 | grpE | SAMN05660991_00052 | SAMN05660991_02868 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.686 |
SEO42026.1 | SEO38678.1 | SAMN05660991_00220 | SAMN05660991_00052 | Molecular chaperone DnaK (HSP70); Belongs to the heat shock protein 70 family. | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | 0.620 |
SEO42026.1 | SEP09018.1 | SAMN05660991_00220 | SAMN05660991_03188 | Molecular chaperone DnaK (HSP70); Belongs to the heat shock protein 70 family. | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | 0.931 |
SEO42026.1 | SEP19122.1 | SAMN05660991_00220 | SAMN05660991_03785 | Molecular chaperone DnaK (HSP70); Belongs to the heat shock protein 70 family. | Hypothetical chaperone protein. | 0.706 |
SEO42026.1 | clpP | SAMN05660991_00220 | SAMN05660991_00908 | Molecular chaperone DnaK (HSP70); Belongs to the heat shock protein 70 family. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.670 |
SEO42026.1 | clpP-2 | SAMN05660991_00220 | SAMN05660991_00909 | Molecular chaperone DnaK (HSP70); Belongs to the heat shock protein 70 family. | ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.670 |
SEO42026.1 | dnaJ | SAMN05660991_00220 | SAMN05660991_00846 | Molecular chaperone DnaK (HSP70); Belongs to the heat shock protein 70 family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.993 |
SEO42026.1 | dnaJ-2 | SAMN05660991_00220 | SAMN05660991_02869 | Molecular chaperone DnaK (HSP70); Belongs to the heat shock protein 70 family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.992 |
SEO42026.1 | grpE | SAMN05660991_00220 | SAMN05660991_02868 | Molecular chaperone DnaK (HSP70); Belongs to the heat shock protein 70 family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.986 |
SEP09018.1 | SEO38678.1 | SAMN05660991_03188 | SAMN05660991_00052 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | 0.816 |
SEP09018.1 | SEO42026.1 | SAMN05660991_03188 | SAMN05660991_00220 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Molecular chaperone DnaK (HSP70); Belongs to the heat shock protein 70 family. | 0.931 |
SEP09018.1 | SEP19122.1 | SAMN05660991_03188 | SAMN05660991_03785 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | Hypothetical chaperone protein. | 0.931 |
SEP09018.1 | clpP | SAMN05660991_03188 | SAMN05660991_00908 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.942 |
SEP09018.1 | clpP-2 | SAMN05660991_03188 | SAMN05660991_00909 | ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.943 |