node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEP02805.1 | dnaA | SAMN05660991_02932 | SAMN05660991_03400 | DnaB-like helicase N terminal domain-containing protein. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.822 |
SEP12048.1 | SEP12423.1 | SAMN05660991_03366 | SAMN05660991_03392 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Chromosome partitioning protein, ParB family; Belongs to the ParB family. | 0.490 |
SEP12048.1 | SEP12547.1 | SAMN05660991_03366 | SAMN05660991_03401 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.736 |
SEP12048.1 | dnaA | SAMN05660991_03366 | SAMN05660991_03400 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.958 |
SEP12048.1 | gyrB | SAMN05660991_03366 | SAMN05660991_03409 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.631 |
SEP12048.1 | recF | SAMN05660991_03366 | SAMN05660991_03403 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.705 |
SEP12423.1 | SEP12048.1 | SAMN05660991_03392 | SAMN05660991_03366 | Chromosome partitioning protein, ParB family; Belongs to the ParB family. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.490 |
SEP12423.1 | SEP12439.1 | SAMN05660991_03392 | SAMN05660991_03393 | Chromosome partitioning protein, ParB family; Belongs to the ParB family. | Chromosome partitioning protein. | 0.999 |
SEP12423.1 | SEP12512.1 | SAMN05660991_03392 | SAMN05660991_03398 | Chromosome partitioning protein, ParB family; Belongs to the ParB family. | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.566 |
SEP12423.1 | SEP12547.1 | SAMN05660991_03392 | SAMN05660991_03401 | Chromosome partitioning protein, ParB family; Belongs to the ParB family. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.528 |
SEP12423.1 | dnaA | SAMN05660991_03392 | SAMN05660991_03400 | Chromosome partitioning protein, ParB family; Belongs to the ParB family. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.846 |
SEP12423.1 | recF | SAMN05660991_03392 | SAMN05660991_03403 | Chromosome partitioning protein, ParB family; Belongs to the ParB family. | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.421 |
SEP12423.1 | rpmH | SAMN05660991_03392 | SAMN05660991_03399 | Chromosome partitioning protein, ParB family; Belongs to the ParB family. | Large subunit ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. | 0.534 |
SEP12439.1 | SEP12423.1 | SAMN05660991_03393 | SAMN05660991_03392 | Chromosome partitioning protein. | Chromosome partitioning protein, ParB family; Belongs to the ParB family. | 0.999 |
SEP12439.1 | SEP12512.1 | SAMN05660991_03393 | SAMN05660991_03398 | Chromosome partitioning protein. | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.548 |
SEP12439.1 | dnaA | SAMN05660991_03393 | SAMN05660991_03400 | Chromosome partitioning protein. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.798 |
SEP12439.1 | rpmH | SAMN05660991_03393 | SAMN05660991_03399 | Chromosome partitioning protein. | Large subunit ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. | 0.492 |
SEP12512.1 | SEP12423.1 | SAMN05660991_03398 | SAMN05660991_03392 | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | Chromosome partitioning protein, ParB family; Belongs to the ParB family. | 0.566 |
SEP12512.1 | SEP12439.1 | SAMN05660991_03398 | SAMN05660991_03393 | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | Chromosome partitioning protein. | 0.548 |
SEP12512.1 | SEP12547.1 | SAMN05660991_03398 | SAMN05660991_03401 | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.799 |